Minimal metastatic disease

Minimal Change Disease.

Minimal change disease (MCD) is a major cause of idiopathic nephrotic syndrome (NS), characterized by intense proteinuria leading to edema and intravascular volume depletion. In adults, it accounts for approximately 15% of patients with idiopathic NS, reaching a much higher percentage at younger ages, up to 70%-90% in children >1 year of age. In the pediatric setting, a renal biopsy is usually ...

Metastatic Crohn's Disease.

Metastatic cutaneous involvement is a rare extraintestinal manifestation of Crohn's disease. Presence of cutaneous noncaseating granulomas that are anatomically noncontiguous in location with a fistula or the gastrointestinal tract is a diagnostic hallmark. We present a case of inflammatory bowel disease initially diagnosed as ulcerative colitis, but later manifesting as intra-abdominal abscess...

Chemotherapy for Metastatic Disease

Bladder cancer occurs with a relatively high incidence in industrial nations. For example, bladder cancer is the fourth most common type of cancer in American men. The estimated U.S. incidence in 2008 was 68,810 cases and the mortality was 14,100 cases (Jemal et al., 2008). Of newly diagnosed bladder cancer cases, approximately 70% 80% will present with non muscle-invasive disease. Among such c...

Metastatic bone disease

OBJECTIVES Guidelines for the management of patients with metastatic bone disease (MBD) have been available to the orthopaedic community for more than a decade, with little improvement in service provision to this increasingly large patient group. Improvements in adjuvant and neo-adjuvant treatments have increased both the number and overall survival of patients living with MBD. As a consequenc...

Radioimmunotherapy of Metastatic Disease